Exploiting the use of DNA single- and double-strand breaking forms of the I-SceI endonuclease to stimulate homologous recombination and gene targeting in budding yeast and in human cells
Taking a DNA molecule into the vicinity of a homologous target gene by a DNA aptamer provides a many-fold enhancement of gene correction frequency at that genetic locus.
Competition may have a high cost for at least one species of tropical seaweed.
John McDonald, professor in the School of Biology and director of the Integrated Cancer Research Center, has also spent many years as the chief scientific officer for Georgia Tech’s Ovarian Cancer Institute.
