Since transgenerational effects require an alteration in the germ line, the link between germline epigenetic modifications and somatic expression of imprinted genes remain poorly understood. Therefore, understanding differences between regulatory mechanisms of imprinted genes in soma versus germ line will provide new insights into how epigenetic marks are transmitted to subsequent generations under normal development and disease conditions.
Selected Publications
- Ajayi, O.O., Peters, S.O., De Donato, M., Mujibi, F.D., Khan W.A., Hussain, T., Babar, M.E., Thomas, B.N., and Imumorin, I.G. 2018. Genetic variation in the N- and C-terminal regions of the bovine DNAJA1 gene in African, Asian and North American cattle. Journal of Genomics 6: 1 – 8.
- De Donato, M., Ruldolfo, H., Peters, S.O., Hussain, T., Babar, M.E., Thomas, B.N, and Imumorin, I.G. 2017. Molecular evolution of type II MAGE genes from ancestral MAGED2 gene and their phylogenetic resolution of basal mammalian clades. Mammalian Genome 28 (9 -10): 443 – 545.
- De Donato, M., Hussain, T., Ruldolfo, H., Peters, SO., Imumorin, I.G. and Thomas, B.N. 2017. Conservation of repeats at the mammalian KCNQ1OT1-CDKN1C region suggests a role in genomic imprinting. Evolutionary Bioinformatics 13: 1 – 14.
- Banabazi M. H., Javaremi, AN, Imumorin, IG, Ghaderi-Zefrei, M., Miraei Ashtiani, SR. 2016. Single nucleotide polymorphisms (SNP) on transcriptome of Holstein cows shared with Illumina bovine SNP arrays. Online Journal of Veterinary Research 20 (3):177-182.
- Okpeku, M. Esmailizadeh, A., Adeola, AC, Shu, L, Zhang, Y., Wang, Y., Sanni, TM, Imumorin, IG, Peters, SO, Zhang, J. Dong, Y and Wang W. 2016. Variation of goat interferon regulatory factor 3 gene and its implication in goat evolution. PLOS ONE 11 (9):e0161962.
- Ibeagha-Awemu, E.A., Akwanji, K.A., Peters, S.O., Imumorin, I.G. and Zhao, X. 2016. High density genome wide genotyping-by-sequencing and association identifies rare SNPs and novel candidate genes influencing cow milk traits. Scientific Reports 10: 6:31109. doi: 10.1038/srep31109.
- Duru, K.C., Guindo, A., Noble J.A., Li, Y, Diallo D.A., Imumorin, I.G. and Thomas, B.N. 2015. Positive selection sweeps and genetic diversity of Knops blood group polymorphisms and association with sickle cell disease. Evolutionary Bioinformatics 11:25-33
- Thakur, T.J., Guindo, A., Cullifer, L.R., Li, Y., Imumorin, I.G, Diallo D.A. and Thomas, B.N. 2014. Endothelin-1 but not endothelial nitric oxide synthase gene polymorphism is associated with sickle cell disease in African children. Gene Regulation and Systems Biology 8: 119-126
- De Donato, M., Peters. S.O., Mitchell, S.E., Hussain, T. and Imumorin, I.G. 2013. Genotyping-by-sequencing: a novel, efficient and cost-effective genotyping method for cattle using next generation sequencing platform. PLOS ONE 8 (5): e62137.
- Peters, S.O., Kizilkaya, K., Fernando, R.L., Garrick, D.J., Pollak, E.J., De Donato, M., Hussain, T. and Imumorin, I.G*. 2013. Application of multivariate heavy-tailed distributions to residuals in the estimation of genetic parameters for growth traits in beef cattle. Journal of Animal Science 91:1552 - 1561.
- Imumorin, I.G*, Kim, H-W., Lee, Y-M., De Koning, D.-J., Arendonk, J.A.M., De Donato, M., Taylor, J.F. and Kim J-J. 2011. Genome scan for parent-of-origin QTL effects on bovine growth and carcass traits. Frontiers in Genetics 2:44.
- Lawton, B.R., Carone, B.R., Obergfell, C., Ferreri, G., Gondolphi, C., VandeBerg, J.L., Imumorin, I.G., O’Neill, R.J. and O’Neill, M.J. 2008. Genomic imprinting of IGF2 in marsupials is methylation dependent. BMC Genomics 9:205.