The Cognitive Motor Control Laboratory investigates the neurophysiological foundations of skilled upper extremity function to advance both clinical practice and public health outcomes. Using cutting-edge neuroimaging, we identify anatomical and physiological circuits that enable effective human-object interactions, providing a scientific basis for rehabilitation strategies. Our clinical research focuses on stroke and upper limb amputation, examining how neural injury disrupts motor control and how surrogate circuits can be harnessed for restorative therapies. By translating these findings into evidence-based interventions, we aim to inform healthcare policy and rehabilitation guidelines that improve access, equity, and quality of care. Our work emphasizes health equity and cost-effectiveness, ensuring that innovative motor recovery approaches are scalable and sustainable across diverse populations and healthcare systems.