My lab investigates how our nervous systems develop and function. In particular, we aim to understand molecularly how neurons build synapses, the specialized junctions that support rapid neuronal communication. Our brains build ~100 trillion synapses during development and continue to build synapses in daily adult life. The location and properties of these synaptic connections fundamentally determine neuronal function. Our recent discoveries have identified biomolecular condensates as central organizers of synapses. We aim to identify the properties of biomolecular condensates that imbue their function in synapse formation and beyond. With a molecular understanding how synapses are formed and function we aim to identify avenues for the regeneration of synapses in neurodegenerative diseases. We approach these questions using live-animal super-resolution imaging of synapse formation, in vitro biochemical reconstitutions, and genetics with CRISPR/Cas9. We primarily use the model organism C. elegans, a nematode worm with a well-defined nervous system.