The Office of Technology Licensing has announced the latest recipients of the Tech Ready Grants, an initiative that helps Georgia Tech faculty advance their innovations toward market readiness. Providing early momentum for promising technologies, the grants help move research toward real-world impact.
“Tech Ready Grants are designed to help researchers take critical steps toward commercialization by supporting early validation and development,” said Mary Albertson, director of Technology Licensing. “These projects represent strong potential for real-world impact across a range of industries.”
This year’s selected projects span areas including advanced manufacturing, biotechnology, medical devices, sustainability, and software systems.
Awardees
Christos Athanasiou
Assistant Professor, Daniel Guggenheim School of Aerospace Engineering
Project: A Scalable In-Situ Durability Platform for Rapid Polymer Qualification
Athanasiou is developing a platform to assess material durability under real-world conditions, helping accelerate validation timelines for high-performance applications.
“What began as a lab-based fracture testing instrument became a way to observe failure under real conditions,” Athanasiou said. “Now, we are working to share that capability beyond a single lab.”
Steve Diggle
Professor, School of Biological Sciences
Project: TAILSTRIKE Platform: Modular Chimeric Tailocin Engineering for Programmable Precision Antibacterials
Diggle is developing a programmable antibacterial platform using engineered protein nanomachines to precisely target harmful bacteria. The approach aims to address antibiotic resistance while enabling more targeted therapeutic applications.
“This grant will support the development of the TAILSTRIKE platform, a modular engineering system that repurposes protein nanomachines which bacteria use in warfare against each other, to create next-generation programmable, precision antibacterials,” Diggle said.
Ellen Yi Chen Mazumdar
Assistant Professor and Woodruff Faculty Fellow, George W. Woodruff School of Mechanical Engineering
Project: High-Efficiency, Fully 3D-Printed Electric Motors
Mazumdar is developing fully 3D-printed electric motors designed for high efficiency and flexible manufacturing across a range of applications.
“The Tech Ready Grant is an exciting opportunity for us to advance our research toward something that can be commercialized as a real product,” Mazumdar said.
Nathan Meraz
Research Engineer, Georgia Tech Research Institute
Project: SCHORTY Technical Document and Market Analysis
Meraz is advancing Scheimpflug Optical Ranging Technology (SCHORTY), a platform that delivers LiDAR-class 3D sensing in a camera-native form factor. The project focuses on identifying high-value commercial applications and validating market opportunities.
“Our platform delivers performance that scales with advances in imaging technology,” Meraz said. “The Tech Ready Grant will support the transition from technical validation to market discovery.”
Carson Meredith
Professor and James Preston Harris Faculty Fellow, School of Chemical and Biomolecular Engineering, and Executive Director, Renewable Bioproducts Institute
Project: Commercialization of Renewable Oxygen and Water Barrier Biodegradable Packaging
Meredith is advancing biodegradable packaging materials that provide strong oxygen and moisture barriers, addressing a key challenge in sustainable packaging.
“My lab carries out research in future packaging materials that can replace problematic single-use plastics,” Meredith said. “This funding will help us translate Georgia Tech developments into practice through prototyping and applied testing.”
William Singhose
Professor, George W. Woodruff School of Mechanical Engineering
Project: Cable Angle Sensing and Control for Improved Crane Safety
Singhose’s team is advancing sensing and control technologies to improve crane safety by monitoring and stabilizing cable angles in real time. The work aims to reduce load swing and enhance operational safety across construction and industrial environments.
“The cable-angle sensing technology we have developed allows crane control systems to detect the early onset of dangerous lifting conditions,” Singhose said. “By identifying when a hoisting cable begins to deviate from vertical, we can take corrective action before uncontrolled swing leads to serious injury or damage.”
Xiaojuan “Judy” Song
Senior Research Engineer, Georgia Tech Research Institute
Project: Smart Dressing for Wound Monitoring
Song is advancing a wearable smart dressing that enables continuous, on-patient monitoring of wound healing progress without disturbing the site. The technology is designed for use in chronic wound care, including diabetic foot ulcers and battlefield applications.
“Tech Ready funding will help advance the technology toward real-world application and define a commercialization pathway,” Song said.
Shuichi Takayama
Professor, GRA Eminent Scholar, and Price Gilbert Jr. Chair in Regenerative Medicine and Engineering, Wallace H. Coulter Department of Biomedical Engineering
Project: Organoid Alternative to Interstitial Lung Disease Toxicity Testing
Takayama’s team is using lab-grown human lung tissue models to evaluate drug toxicity, offering a more accurate and scalable alternative to traditional primate models.
“This system fills a critical gap where species differences limit the use of traditional models,” Takayama said.
Jun Xu
Professor, School of Computer Science
Project: Research Into Applications and API for METTLE
Xu is advancing METTLE, a novel streaming erasure code designed for high-speed networking systems, with a focus on improving data reliability and efficiency.
“This funding will support the commercialization readiness of METTLE,” Xu said.
About Tech Ready Grants
Tech Ready Grants is an Office of Technology Licensing program that provides early-stage funding to faculty to support prototype development, validation, and market assessment. The program helps position technologies for licensing, startup formation, and industry partnerships.
By supporting these critical early steps, Tech Ready Grants strengthens the pathway from research to real-world impact across Georgia Tech’s innovation ecosystem.
This year, eight Georgia Tech students have been awarded the prestigious Fulbright Scholarship, and four have been named as alternates. The Fulbright U.S. Student Program, sponsored by the U.S. Department of State and the Fulbright Foreign Scholarship Board, provides opportunities for students and professionals to study, conduct research, and teach abroad while promoting mutual understanding between the United States and other countries.
Among this year’s recipients are several members of Georgia Tech’s Class of 2026, as well as a doctoral student.
Divya Tadanki, who graduated with a bachelor’s degree in neuroscience, expressed her enthusiasm about her future research plans. “Through the Fulbright,” she explained, “I’ll be working in the Netherlands to research the predictors of preterm labor. I’m very excited to delve deeper into my research interests with people from across the globe.”
After double-majoring in biology and Spanish, Sonali Kaluri is headed to Spain to study the health of migrant workers under the digital platform economy. “With the Fulbright Scholarship,” she said, “I will conduct research on the gig economy and its implementation into health systems in Spain at the Barcelona Institute for Global Health.”
Having earned his bachelor’s degree in biochemistry, Seth Kinoshita will be working with Professor Urszula Stachewicz in the Electrospun Nanofibers group at AGH University of Science and Technology in Krakow, Poland. “I am excited to connect with my Polish heritage, explore Eastern Europe, and strengthen my research background,” he remarked. “Thank you to Dr. Brunner for their endless support during this process, and I encourage everyone to consider applying for fellowships while at Tech!”
Zachary Beddingfield, who graduated with a bachelor’s degree in biology, will travel to Germany as a Fulbright Research Scholar where he will explore the intersection of his two passions: biology and machine learning. “I will be learning how to implement Protein Language Models to design de novo proteins that are unrelated to any proteins found in nature,” he explained. “I hope to design a de novo protease that degrades a specific protein responsible for most symptoms in human urinary tract infections, as proof of concept that these tools can be used to target a broad range of pathogenic proteins.”
With a bachelor’s degree in neuroscience, Diya Chutani will continue her academic journey as a Fulbright Canada recipient, beginning a Ph.D. in Neuroscience at the University of Western Ontario’s Music and Neuroscience Lab. “To be able to return to the music cognition community I discovered in Ontario last summer,” she noted, “where there is value in both my musical and scientific background, is a privilege I am so grateful for. I am eager to begin contributing meaningfully to research that can enhance music-based interventions for neurodegenerative diseases.”
Anya Martin, who is currently pursuing a Ph.D. in Interactive Computing, plans to focus on weather and climate forecasting in India. “I plan to use the Fulbright to do social-scientific work with meteorologists in India using AI machine learning (AI/ML) methods for weather and climate forecasting,” she said, reflecting on her selection for the award. “AI/ML methods have a lot of promise for meteorology, but we will see how the methods pan out in practice.”
Since 1946, the Fulbright Program has provided nearly 450,000 talented and accomplished individuals with the opportunity to exchange ideas, build people-to-people connections, and work to address complex global challenges. More than 2,000 Fulbright U.S. Students — including recent college graduates, graduate students, and early career professionals — pursue graduate study, conduct research, or teach English in schools abroad each year.
Fulbright is a program of the U.S. Department of State, with funding provided by the U.S. Government. Participating governments and host institutions, corporations, and foundations around the world also provide support to the Program, which operates in over 160 countries. In the United States, the Institute of International Education implements the Fulbright U.S. Student and U.S. Scholar Programs on behalf of the U.S. Department of State.
For more information about the Fulbright Program or other nationally competitive awards, visit the Prestigious Fellowships Advising website or contact the team at fellowshipsadvising@gatech.edu.
A Georgia Tech-led project advancing coastal resilience and ecosystem restoration has been selected for the inaugural Climate Resilience Fund cohort, awarded by Revive & Restore. The award is one of ten in a new $3.4 million fund to leverage genetic rescue for marine and coastal ecosystems under threat from climate shifts.
Led by Joel E. Kostka, Tom and Marie Patton Distinguished Professor and director of Georgia Tech for Georgia’s Tomorrow (GT²), the research effort will help restore coastal salt marshes through AI-enabled micropropagation and developing probiotics for plants. It is the only salt marsh-focused effort funded nationally in the cohort.
The award supports both the development of more climate-resilient salt marsh plants, as well as new capacity for coastal restoration in Georgia — an effort that aligns closely with GT²’s mission to connect research, innovation, and community needs to address critical environmental and community challenges.
Healthy Coasts
Salt marshes are among Georgia’s most important natural resources, helping buffer communities from storms, support fisheries, and sustain coastal economies. Yet the state currently lacks a reliable source of salt marsh seedlings needed for large-scale restoration.
The funded project addresses that gap by advancing the production of hardier marsh plants and laying the groundwork for a broader restoration economy.
“The opportunity here is to build something that doesn’t currently exist in Georgia — a scalable, science-driven supply of salt marsh plants for safer, healthier coastal communities and ecosystems,” Kostka says. “By combining biotechnology, ecology, and partnerships across the region, we are accelerating coastal resilience while supporting long-term environmental and economic benefits.”
Kostka will work with project co-researchers Else-Marie Ulrika Egertsdotter (Georgia Tech Renewable Bioproducts Institute) and Caitlin Petro (Georgia Tech Biological Sciences), Heather Joesting (Georgia Southern University), Emily Coffey and Lauren Eserman-Campbell (Atlanta Botanical Garden), and Sydney Williams (University of Georgia and Georgia Sea Grant) — along with several anticipated regional partners, including University of Georgia Marine Institute, GA/SC/NC Departments of Natural Resources, Southeastern Plant Conservation Alliance, and Bald Head Island Conservancy.
The team will create a “Climate-Ready Spartina Toolkit” with automated plant tissue culture, AI-based screening tools, a culture collection that serves as probiotics for plants, a seed bank and library of preserved plant materials, step-by-step instructions for successful growing, and ready for regional deployment.
The project also continues the evolution of Kostka’s collaborative research Egertsdotter and the Georgia Tech Renewable Bioproducts Institute. “RBI shares the goal of using biotechnology to produce climate-resilient plants that benefit society,” Kostka says. “Their expertise in plant tissue culture and automation make this work possible. It also is a great example of collaboration between GT Sciences and Engineering — the automation of plant tissue culture was developed by mechanical engineers in RBI.”
Regional Resilience
The new award builds on growing momentum for Georgia Tech for Georgia’s Tomorrow and its expanding network of collaborators focused on coastal resilience. Based in the College of Sciences, GT² is designed to align discovery science with technological innovation and data-driven tools to deliver practical solutions for communities across the state.
In April, GT² launched a formal research fund and partnership with the Bald Head Island Conservancy (BHIC), connecting Georgia Tech researchers with BHIC’s Johnston Center for Coastal Sustainability in North Carolina to advance shared work in coastal sustainability, ecosystem health, and environmental resilience.
The partnership combines BHIC’s applied, field-based conservation work with Georgia Tech’s strengths in technological innovation and data analysis, creating new opportunities for graduate research, community engagement, and real-world implementation.
Better Together
These “all hands on deck” approaches reflect a broader strategy to scale tangible solutions across regional ecosystems by connecting researchers and partners with community stakeholders.
“Together, we hope these projects will demonstrate that genetic rescue is a powerful lever for the blue carbon ecosystems that underpin both ecological and human communities in the face of climate change,” said Liv Liberman, Director of Ocean and Climate at Revive & Restore and program manager for the Climate Resilience Fund.
The efforts reflect GT²’s goal of creating pathways from research to implementation, working across sectors to deliver measurable outcomes for the southeastern environment and its communities.
“This award recognizes the kind of integrated, real-world research that GT² is built to deliver,” says Kostka. “We’re bringing together researchers, agencies, and community partners to move from science to scalable solutions — especially along southeastern coasts, where the need is urgent and the opportunities are significant.”
###
About Georgia Tech for Georgia’s Tomorrow
Georgia Tech for Georgia’s Tomorrow (GT²) is a College of Sciences–based initiative that connects discovery science, innovation, and partnerships to address pressing challenges in environmental and community resilience across Georgia. The initiative works with state agencies, industry, non-profits, and local communities to develop solutions that improve quality of life and strengthen the state’s future.
About Revive & Restore
Revive & Restore is a nonprofit conservation organization that develops and promotes genetic rescue technologies to protect and restore endangered and extinct species. Founded in 2012 by Stewart Brand and Ryan Phelan, the organization works across birds, mammals, coral, and marine ecosystems to demonstrate that biotechnology is an essential tool in the conservation toolkit.
Five Georgia Tech students have been awarded Fulbright Canada-Mitacs Globalink Research Internships, which support U.S. undergraduates pursuing advanced summer research at universities across Canada. This year’s cohort, including Alysa Jordan, Syona Gupta, Samuel Woolsey, Swathi Mugundu Pradeep, and Nidhi Shenoy will contribute to projects spanning neurodevelopment, renewable energy, hydrogen storage, carbon sequestration, and more.
Together, they reflect Georgia Tech’s deep commitment to undergraduate research, global engagement, and addressing some of the world’s most pressing scientific and environmental challenges.
From the College of Sciences:
Alysa Jordan
This summer, Alysa Jordan will join the Seib Laboratory at the University of Prince Edward Island to study how maternal antibiotic exposure affects the gut microbiome, placenta, and ultimately fetal neurodevelopment. A neuroscience major, her work integrates immunohistochemistry to identify structural changes in maternal and fetal brain tissue, as well as mass spectrometry to analyze how antibiotics alter the availability of key metabolites. Jordan hopes her research will contribute to a deeper understanding of prenatal health and early developmental outcomes.
“Go after what you’re interested in,” she said, advising future applicants, “and lean on the resources provided by Georgia Tech and the Prestigious Fellowships office.”
Nidhi Shenoy
Biochemistry student Nidhi Shenoy will be conducting her research at Dalhousie University Medical School in Saint John, New Brunswick. She will investigate how transcription factor E3 (TFE3) promotes cellular waste clearance to support mitochondrial and lysosomal health in heart cells under obesity and diabetes. Her work aims to identify targetable pathways to improve cardiac metabolism, survival, and function.
Shenoy expressed how closely the opportunity aligns with both her personal interests and professional goals.
“As someone who loves to travel around the world,” she said, “this opportunity is incredibly exciting and valuable as I can experience research and professional workplace environments globally. International education and experience are so integral to shaping who I am.”
This month, nineteen Georgia Tech faculty and researchers were honored by the Board of Regents of the University System of Georgia (USG) with 2026 Regents’ Awards. These distinctions, awards, and reappointments recognize excellence in teaching, research, innovation, and entrepreneurship across the USG.
The recipients were approved during the University System of Georgia’s 2026 awards cycle, recognizing individuals whose sustained contributions have made a significant impact on their fields, their students, and the broader research and education community.
This cohort includes faculty who represent all six schools across the College of Sciences.
2026 Regents’ Award Recipients and First Renewals
College of Sciences
- Randall Engle, School of Psychology (Regents’ Professor)
- Thomas Orlando, School of Chemistry and Biochemistry and School of Physics (Regents’ Professor Renewal)
- Rafael L. Bras, School of Earth and Atmospheric Sciences and School of Civil and Environmental Engineering (Regents’ Professor Renewal)
(Joint with College of Engineering)
- Santosh Vempala, School of Computer Science with courtesy appointments in Mathematics and Industrial and Systems Engineering (Regents’ Professor)
(Joint with College of Computing and College of Engineering)
College of Sciences second renewal approved by Georgia Tech President Ángel Cabrera:
- Jeffrey Skolnick, School of Biological Sciences
View all nineteen recipients across the Institute here.
About the Regents’ Awards
The Regents’ Awards are among the University System of Georgia’s highest honors, recognizing sustained excellence, national distinction, and long-term impact by faculty and researchers across the state’s public institutions.
Two School of Biological Sciences assistant professors, Nathan McDonald and Farzaneh Najafi, have received Curci Foundation grants to support new research in their fields.
The Shurl and Kay Curci Foundation funds science-based projects with an emphasis on advancing a healthy and sustainable future for humans, focusing on early-stage research with far-reaching and lasting implications.
“This is a special program that supports junior faculty with particular creativity,” says School of Biological Sciences Chair Todd Streelman. “The best part for me is that representatives from the Curci Foundation visit our campus and conduct in-person interviews, showing they value both the projects and the young scientists.”
Nathan McDonald: Understanding Synapses and Engineering their Repair
The McDonald Lab studies the fundamental biology of synapses, the tiny structures that allow neurons to communicate. Their research focuses on understanding how the nervous system and brain develop, specifically how hundreds of billions of neurons form and connect through trillions of synapses – and how they continue to change throughout adult life.
“What’s exciting about the grant is that it allows us to apply that knowledge and explore whether and how we might control synapse formation,” explains McDonald.
The McDonald Lab will examine whether the molecular processes neurons use to build synapses during early development can be reactivated later in life.
If successful, the new research could have implications for aging and neurodegenerative conditions in which synapses are lost, potentially revealing ways to repair specific synapses and restore their function.
“Many researchers are interested in repairing or regenerating synapses. Most approaches so far have focused on pharmaceuticals – using drugs to influence synaptic strength. What makes our approach unique is that we are trying to leverage the developmental machinery that neurons already have,” he explains.
McDonald and his team are working with Caenorhabditis elegans, a microscopic roundworm widely used in neuroscience research. The organism offers a simplified, tractable system for examining how synapses are built, dismantled, and potentially rebuilt.
“If we can demonstrate proof of concept in a simple nervous system, that opens the door to scaling these approaches to more complex models,” explains McDonald.
He plans to use the Curci funds to support students and staff as they explore these new methods for engineering synapse formation.
“The work has the potential to be developed into something more translational and applicable to disease,” says McDonald. “These sources of funding are incredibly important for launching new research directions.”
Farzaneh Najafi: Exploring Sleep and the Cerebellum’s Role in Cognitive Health
The Farzaneh Najafi Lab examines predictive processing, how the brain makes and learns predictions about the world. Najafi’s research focuses on deepening understanding of how sleep supports learning and cognitive health across the lifespan.
Najafi’s Curci-funded research will examine how the brain uses sleep to reorganize itself after learning, with a particular focus on the cerebellum, a region that contains nearly 80 percent of the brain’s neurons. By identifying changes in cerebellar activity during sleep, her work has the potential to improve early detection of neurological disorders.
“We know that sleep stabilizes memories in areas like the cortex and hippocampus, but we know very little about what sleep does in the cerebellum,” says Najafi. “This grant allows us to bring sleep, cerebellar circuitry, and learning together.”
Najafi and her team will combine behavioral experiments with high-resolution imaging to study how cerebellar circuits and synapses change across wake and sleep.
“We’re looking at cerebellar activity during sleep at the circuit and synapse level to see how learning-related changes unfold,” explains Najafi.
In some cerebellar disorders, sleep disturbances can appear five to 10 years before motor symptoms begin. By identifying early changes in cerebellar activity during sleep, Najafi’s research could help pinpoint neurological disease at a stage when intervention may still be possible.
Curci funding will allow Najafi’s lab to collect foundational data needed to establish the first mechanistic links between sleep, cerebellar activity, and long-term brain health.
“Many traditional funding mechanisms are hesitant to support these kinds of higher‑risk directions, especially early on, but this award makes it possible to pursue a new and promising line of inquiry,” says Najafi.
In recognition of her extraordinary teaching, outreach, and mentoring activities, Emily Weigel has been awarded the Eugene P. Odum Award for Excellence in Ecology Education by the Ecological Society of America (ESA). Each year, the award celebrates a singleone individual’s sustained, outstanding work in ecology education.
“I’m honored to receive the 2026 Odum Award,” says Weigel, who is a senior academic professional in the School of Biological Sciences. “Georgia Tech is widely recognized for its research excellence, but teaching is mission-critical to the ways we serve the public good. This award reflects the incredible work happening in our classes and communities that drives science, and science education, forward.”
Weigel is among 10 individuals selected nationwide for annual ESA awards. “This year’s award recipients have each contributed something important to ecology, often in very different ways,” says ESA President Peter Groffman. “These are ecologists whose efforts have shaped the field, supported colleagues and created opportunities for others. I’m glad to see that kind of work acknowledged.”
About Emily Weigel
Weigel’s work focuses on improving biology education by examining how student backgrounds, values, and instructional practices shape learning outcomes. Her impact spans K–12 students, undergraduates, graduates, and members of the Atlanta community.
Known for her teaching innovations, she has pioneered new courses in biology, ecology, and statistics, and is also a leader in the Vertically Integrated Projects program at Georgia Tech.
From studying the dynamics of flu, to using drone aerial footage to monitor Georgia Tech’s changing landscape, to a long-term project monitoring the trees of the Campus Arboretum, Weigel shares that “students thrive when they develop skills through real-world experiences."
Weigel has also creatively infused the traditional “nature” topics and fieldwork found in ecology curricula with modern technology and programming skills used in research. “Effectively introducing professional skills, like programming in the language R, is innovative nationally,” she says. By making R, an open-source programming language, more accessible, “we’re preparing undergraduates for success in graduate school and their careers, and empowering them to learn other programming languages in the future.”
In addition to teaching, Weigel plays a central role in mentoring and supporting students across the Institute. She serves as the undergraduate academic advisor for around one-sixth of Georgia Tech’s Biology majors, mentors graduate and undergraduate teaching assistants, and is an instructor for the “Tech to Teaching” capstone course in the Center for Teaching and Learning.
Saumya Jain, assistant professor in the School of Biological Sciences, has been named a 2026 Searle Scholar and awarded a $450,000 research grant. His research focuses on how connections in the brain form during development and what goes wrong in conditions such as autism and schizophrenia.
Jain is one of 15 scientists selected this year for “their promise to change their fields by solving nature’s puzzles in a broad range of fields and develop next-generation technologies that can reveal biological function,” according to a Searle Scholars Program press release.
“We are honored to be part of the Searle Scholars Program,” Jain says. “For a young lab with ambitious goals, this kind of recognition means everything. It gives us the confidence and resources to pursue high-risk, high-reward questions that could one day make a real difference for people affected by neurodevelopmental disorders.”
Jain received his Ph.D. in molecular and cellular biology from the University of Arizona and completed his postdoctoral work at the University of California, Los Angeles. He joined Georgia Tech in 2024.
Biology major Sonali Kaluri is a STEM expert. Spanish major Sonali Kaluri is a language and culture expert.
Put the two together and you have a sharply educated researcher with a passion for healthcare. Kaluri is headed to Barcelona after graduation this Spring as a Fulbright Scholar to study the health of migrant workers under the digital platform economy. She plans to later embark on a career in medicine.
It’s something she says she couldn’t have done without her experiences at the Ivan Allen College of Liberal Arts.
“You need to have a deep understanding of people and the systems that surround us to be able to effectively and ethically help people as a physician,” Kaluri said.
Kaluri’s Applied Languages and Intercultural Studies degree from the School of Modern Languages helped shape that understanding, including through classes studying Spanish literature.
“Literature is such an important window into the lives of people different from you,” Kaluri said. “Studying another language’s great works is an excellent way to understand the experiences of different people and build that empathy, which translates to real life for me in being able to better connect with the people I meet.”
Kaluri, who was fluent in her parents’ languages of Telugu and Kannada before arriving at Georgia Tech, had always wanted to combine language training with her work in healthcare.
“Early in high school and college, I would shadow doctors, and if they had a patient that couldn’t speak English, I’d be able to follow along with the conversation even without an interpreter using my knowledge from high school Spanish classes,” Kaluri said. “I figured that one day as a doctor, it would be cool to be able to talk directly to a larger number of patients without needing an interpreter and to be able to build greater rapport with patients. That was the spark for why I wanted to pursue more rigorous study of Spanish.”
Her interest in medicine derives from seeing how cultural norms around gender and caregiving can shape and even sideline women’s own healthcare needs.
“I realized that was a big part of why I wanted to pursue medicine — to advocate for people on a deeper level, to try to bridge these gaps that I've noticed in research, in the clinic, et cetera,” Kaluri said.
Kelly Comfort, one of Kaluri’s Spanish professors, said Kaluri’s success shows what’s possible with a combined STEM and liberal arts education.
“Sonali is the kind of student who proves that the humanities are not separate from science and medicine — they strengthen them. Her ability to think critically about culture, identity, and social systems through her ALIS major has shaped her into a more thoughtful future healthcare professional,” Comfort said.
“She is not only highly skilled in pre-health and pre-medicine fields, but she is also multilingual, interculturally competent, empathetic, reflective, and prepared to improve the human condition across cultures, languages, and borders,” Comfort said.
The United States Department of Agriculture (USDA) has awarded $2 million to a team of Georgia Tech and Georgia Tech Research Institute (GTRI) researchers to develop a first-of-its-kind vaccine pill for bird flu.
For decades, bird flu was uncommon in the U.S., but that has changed. In the past several years, epidemics have threatened poultry and dairy cattle operations across the country. Higher egg prices, driven largely by bird flu-related supply disruptions, have cost American consumers billions of dollars in losses.
“The H5N1 strain of the bird flu, which has driven recent and current outbreaks, is a highly lethal virus that kills domestic chickens and other bird species in droves,” said David Pattie, GTRI research scientist and branch chief. “It can easily jump from birds to other animal species — and sometimes to humans.”
The research team will leverage artificial intelligence (AI) to design and test a probiotic avian flu vaccine that, if successful, could be served to chickens in their feed. Currently, vaccinating a flock means individually injecting every bird.
“We’re focusing on live bacterial vaccines, which means the vaccine comes from living bacteria you swallow, instead of an injection,” said Mike Farrell, GTRI principal research scientist and the project’s lead investigator.
“These probiotic vaccines would help protect birds and livestock from flu-like infections and lower the risk of those viruses spreading to humans,” he added.
In addition to Farrell and Pattie, the team includes researchers from an array of disciplines across the Institute: Faramarz Fekri, professor and John Pippin Chair in the School of Electrical and Computer Engineering; JC Gumbart, Dunn Family Professor in the School of Physics; Brian Hammer, associate professor in the School of Biological Sciences; and Anton Bryksin, director of the Molecular Evolution Core at the Parker H. Petit Institute for Bioengineering and Bioscience.
Building on Human Influenza Research
The project builds on Farrell’s ongoing research into developing probiotic vaccine adjuvants for human influenza. The goal is to use probiotic bacteria — the “good bacteria” found in foods like yogurt — to help create immunity for the flu vaccine.
If the researchers can get probiotic bacteria to display pieces of the flu virus (called antigens) on their surface, then they could be swallowed like a normal probiotic pill.
“The gut is a great place for building immunity. When these bacteria reach the gut, your body would recognize the virus pieces on the bacteria and start building flu antibodies,” Farrell explained. “That way, when the chickens get exposed to flu, their immune system would already be prepared to fight it.”
Putting AI to the Test
“The idea behind this oral bird flu vaccine is to leverage artificial intelligence and the vast historical database for H5N1 available to us, because it's a very well-studied virus,” Farrell said. “There is a ton of structural data out there.”
Gumbart is an expert in protein modeling and simulation. Part of his role is figuring out the best design for a viral protein piece (antigen) — one that looks and behaves like the real virus protein, so it triggers the right immune response. To do this, he will combine Fekri’s AI-generated predictions with computer modeling.
“That’s where my team adds real value,” Gumbart said. “We use simulations to test how stable and realistic these protein designs are, which allows us to choose the best ones for lab experiments.”
AI has already identified new medicines and antibiotics by studying chemical databases. If the team can use AI to help design virus proteins for vaccines, it could transform how vaccines are made.
Pattie says that any viral infectious disease with a high mortality rate has the potential to become a national security threat. “At that point, developing countermeasures becomes exceedingly important from a national security perspective,” he said.
This is the first time several of the team members are working on poultry research. For Gumbart, the project is a full-circle moment.
“I grew up in rural Illinois, and as a kid, one of my daily chores was to take care of chickens, and I kind of hated it,” he said. “It is some sort of universal irony that I am back to taking care of chickens again.”
